S22AG Rabbit Polyclonal Antibody, 50ul Adeno-associated Virus Packaging This protein contains an I

This protein contains an I domain

It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues

Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors

The protein is a cancer-associated antigen that can stimulate autologous T-cell responses| and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies| including diffuse large B-cell lymphoma

S22AG Rabbit Polyclonal Antibody, 50ul Adeno-associated Virus Packaging This protein contains an IThis gene encodes a member of the organic zwitterion transporter protein family which transports carnitine. The encoded protein has also been shown to transport anticancer drugs like bleomycin (PMID: 20037140) successful treatment has been correlated with the level of activity of this transporter in tumor cells.