HES5 Polyclonal Antibody, 20ul Recombinant Ab Production it deacetylates p53 and modulates

it deacetylates p53 and modulates its effect on cell growth and apoptosis

Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene

This gene is part of a 500 kb inverted duplication on chromosome 5q13

Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known

HES5 Polyclonal Antibody, 20ul Recombinant Ab Production it deacetylates p53 and modulatesThis gene encodes a member of a family of basic helix loop helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer.