PAPP2 Polyclonal Antibody, 50ul Cell Culture Dishes The protein encoded by SMO

The protein encoded by SMO (smoothened

and an N-terminal regulatory domain (Habc)

This gene is involved in epidermal differentiation| and it is expressed at high levels in normal and psoriatic skin| but not in cultured keratinocytes or in any other tested cell types or tissues

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4|5-bisphosphate to 1D-myo-inositol 1|4|5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor

PAPP2 Polyclonal Antibody, 50ul Cell Culture Dishes The protein encoded by SMOThis gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin like growth factor binding protein 5 and is thought to be a local regulator of insulin like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants.