PGE synthase Polyclonal Antibody, 100ul Electronic Pipette This protein is involved in

This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF)

Double PHD fingers 2encoded by DPF2 is a member of the d4 domain family

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and trace-amine receptor activity

Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease

PGE synthase Polyclonal Antibody, 100ul Electronic Pipette This protein is involved inProstaglandin E synthase encoded by PTGES is a glutathione dependent prostaglandin E synthase. The expression of PTGES has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain