NPC2 Rabbit Polyclonal Antibody, 100ul Glassware Sets Binds to the consensus calcium-response

Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence

This gene has been shown to induce cell apoptosis and may function in various developmental stages

Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis

and a short C-terminal cytoplasmic tail

NPC2 Rabbit Polyclonal Antibody, 100ul Glassware Sets Binds to the consensus calcium-responseThis gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal lysosomal system. Mutations in this gene have been associated with Niemann Pick disease type C2 and frontal lobe atrophy.