AES Polyclonal Antibody, 100ul Mammalian Expression Defects in this gene are

Defects in this gene are the cause of LIG4 syndrome

Reduced expression and rearrangement of this gene have been detected in various cancers

Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells

The product of this gene is a transcription factor that is rapidly induced after temperature stress and binds heat shock promoter elements (HSE)

AES Polyclonal Antibody, 100ul Mammalian Expression Defects in this gene areThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms