IRE1 Alpha/Beta Polyclonal Antibody, 100ul Capsule Filter Two transcript variants encoding different

Two transcript variants encoding different isoforms have been found for this gene

and that this isoform is localized in the peroxisomes

The human genome contains a pseudogene similar to the 3' half of this gene

The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails

IRE1 Alpha/Beta Polyclonal Antibody, 100ul Capsule Filter Two transcript variants encoding differentInduces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro apoptotic. Appears to play no role in the unfolded protein response, unlike closely related proteins.