Raf-1 Polyclonal Antibody, 20ul[BT-AP13534] Cell Labeling & Imaging The encoded protein binds RNA

The encoded protein binds RNA and interacts with two other EJC core components

Phosphorylation of Ser-51 does not affect DNA repair

lacking the N-terminal hydrophobic region but retaining the same activity

YAP/TEAD complexes regulate the expression of genes involved in cell proliferation and apoptosis

Raf-1 Polyclonal Antibody, 20ul[BT-AP13534] Cell Labeling & Imaging The encoded protein binds RNAThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.