p53 Polyclonal Antibody, 100ul[BT-AP06826] Pipette Holder PTM:Palmitoylation is critical for proper

PTM:Palmitoylation is critical for proper membrane localization and signaling

4-dienoyl-CoA to yield trans-3-enoyl-CoA

and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease

Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1)

p53 Polyclonal Antibody, 100ul[BT-AP06826] Pipette Holder PTM:Palmitoylation is critical for properTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.