IMP cyclohydrolase Monoclonal Antibody, 100ul Lentiviral Packaging Mitogen-activated protein kinase kinase kinase

Mitogen-activated protein kinase kinase kinase MLK4 is a negative regulator of TLR4 signaling

Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors

These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b)

contributing to both cell proliferation and survival

IMP cyclohydrolase Monoclonal Antibody, 100ul Lentiviral Packaging Mitogen-activated protein kinase kinase kinaseThis gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA ribosiduria.