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Phospho-B23 (T234) Polyclonal Antibody, 50ul Primary Antibodies AASS encodes a bifunctional enzyme

SKU: 15131101028

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Phospho-B23 (T234) Polyclonal Antibody, 50ul Primary Antibodies AASS encodes a bifunctional enzymeNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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Description

AASS encodes a bifunctional enzyme (aminoadipate-semialdehyde synthase) that catalyzes the first two steps in the mammalian lysine degradation pathway

Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene

Alternatively spliced transcript variants encoding distinct isoforms have been found for GOSR1

aspartate transcarbamylase

Phospho-B23 (T234) Polyclonal Antibody, 50ul Primary Antibodies AASS encodes a bifunctional enzymeNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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