PIAS 1 Polyclonal Antibody, 50ul Buffers & Solutions Mutations in this gene are

Mutations in this gene are associated with ectodermal dysplasia

The encoded protein forms a complex with alpha-2

Neuromedin-U is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain

Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor

PIAS 1 Polyclonal Antibody, 50ul Buffers & Solutions Mutations in this gene arePIAS1 encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Protein inhibitor of activated STAT 1 plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript