SPZ1 Polyclonal Antibody, 100ul Mechanical Pipette Genetic variation in this gene

Genetic variation in this gene influences susceptibility to occlusive vascular disease

and modulation of cell growth

The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily

A full-length representative protein consists of an extracellular region| composed of three immunoglobulin-like domains| a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain

SPZ1 Polyclonal Antibody, 100ul Mechanical Pipette Genetic variation in this geneSPZ1 (spermatogenic leucine zipper 1) encodes a bHLH zip transcription factor which functions in the mitogen activate protein kinase (MAPK) signaling pathway. Because of its role in the upregulation of cell proliferation and tumorigenesis, SPZ1 may serve as a target for Ras induced tumor treatments.