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GRK 1 Polyclonal Antibody, 100ul Reservoirs This gene encodes a nuclear

SKU: 16748237154

4.4
SEK123.75 SEK146.75

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GRK 1 Polyclonal Antibody, 100ul Reservoirs This gene encodes a nuclearGRK1 encodes a member of the guanine nucleotide binding protein (G protein) coupled receptor kinase subfamily of the Ser Thr protein kinase family. Rhodopsin kinase phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type 2).

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Description

This gene encodes a nuclear protein with three C2H2-type zinc fingers| and functions as a transcriptional repressor

q11) with immunoglobulin gene regions

Positively regulates the beta-catenin pathway (canonical Wnt signaling pathway) and is required for MCC-mediated repression of the beta-catenin pathway (PubMed: 24824780)

It could also be involved in chondrodysplasias or other cartilage disorders

GRK 1 Polyclonal Antibody, 100ul Reservoirs This gene encodes a nuclearGRK1 encodes a member of the guanine nucleotide binding protein (G protein) coupled receptor kinase subfamily of the Ser Thr protein kinase family. Rhodopsin kinase phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type 2).

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