ROP1A Rabbit Polyclonal Antibody, 100ul Thermal Control A similar gene disrupted in

A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation

Studies suggest this is a cancer suppressor gene

The protein encoded by this gene is an activator of RHO-type GTPases

Down's syndrome

ROP1A Rabbit Polyclonal Antibody, 100ul Thermal Control A similar gene disrupted inThe protein encoded by this gene is found in the fibrous sheath of spermatazoa where it interacts with rhophilin a Rho GTPase binding protein. The encoded protein also can bind an A kinase anchoring protein (AKAP110) and a calcium binding tyrosine phosphorylation regulated protein (CABYR). This protein may be involved in sperm motility and has been shown to be a cancer testis antigen in hematologic malignancies. Several transcript variants some