Nibrin(Phospho Ser278) Polyclonal Antibody, 100ul Plasmid Preparation May form a cell surface

May form a cell surface vasopressin receptor

Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11)

Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling

This cytokine has overlapping signaling functions with TNF

Nibrin(Phospho Ser278) Polyclonal Antibody, 100ul Plasmid Preparation May form a cell surfaceMutations in this gene are associated with Nijmegen breakage syndrome an autosomal recessive chromosomal instability syndrome characterized by microcephaly growth retardation immunodeficiency and cancer predisposition. The encoded protein is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint