Phospho-Catalase (Y386) Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Defects in complex I are

Defects in complex I are a common cause of mitochondrial dysfunction

The enzyme encoded by this intronless gene is a beta-1

POU4F1 (POU class 4 homeobox 1) encodes a member of the POU-IV class of neural transcription factors

Allelic variants of this gene have been associated with obesity

Phospho-Catalase (Y386) Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Defects in complex I areCAT (catalase) encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late onset diseases such as