PABP4 Polyclonal Antibody, 50ul Modification Enzymes Chloride channel 4 has an

Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster

The active site residues of carboxypeptidases A and B are conserved in this protein

The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis

Several alternatively spliced transcript variants have been found for this gene

PABP4 Polyclonal Antibody, 50ul Modification Enzymes Chloride channel 4 has anPoly(A) binding proteins (PABPs) bind to the poly(A) tail present at the 3 prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation induced T cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5 fold. PABPC4 contains 4 RNA binding domains and proline rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be