BMAL1 Monoclonal Antibody, 50ul Cell Culture This transmembrane protein localizes to

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BMAL1 Monoclonal Antibody, 50ul Cell Culture This transmembrane protein localizes toThe protein encoded by this gene is a basic helix loop helix protein that forms a heterodimer with CLOCK. This heterodimer binds E box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK ARNTL complexes. Defects in this gene have been linked to

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