NF-H Polyclonal Antibody, 50ul Deep Well Plates Disruption of the TGF-beta/SMAD pathway

Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers

and endocrine dysfunction (SSMED)

Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index

A second ligand| the heditary hemochromatosis protein HFE| competes for binding with transferrin for an overlapping C-terminal binding site

NF-H Polyclonal Antibody, 50ul Deep Well Plates Disruption of the TGF-beta/SMAD pathwayNeurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. NEFH encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been