TIRAP Polyclonal Antibody, 100ul Monoclonal Antibodies PubMed: 21050863

PubMed: 21050863

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Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so

The encoded protein may play a role in energy homeostasis and regulation of body weight

TIRAP Polyclonal Antibody, 100ul Monoclonal Antibodies PubMed: 21050863The innate immune system recognizes microbial pathogens through Toll like receptors (TLRs), which identify pathogen associated molecular patterns. Different TLRs recognize different pathogen associated molecular patterns and all TLRs have a Toll interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The TIR domain containing adaptor protein encoded by TIRAP is a TIR adaptor protein involved in the TLR4 signaling pathway of