PHLD Polyclonal Antibody, 50ul Reagent Reservoirs Expression of this protein is

Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation

The encoded preproprotein is proteolytically processed to generate the mature enzyme

a class of enzyme that catalyzes the release of fatty acids from phospholipids

with or without motor neuropathy

PHLD Polyclonal Antibody, 50ul Reagent Reservoirs Expression of this protein isMany proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma