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MUC5B Polyclonal Antibody, 50ul Liquid Handling &Storage The high mobility group nucleosome

SKU: 22176335838

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MUC5B Polyclonal Antibody, 50ul Liquid Handling &Storage The high mobility group nucleosomeThis gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS

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Description

The high mobility group nucleosome binding domain 1 encoded by HMGN1 binds nucleosomal DNA and is associated with transcriptionally active chromatin

where the mature form is found

It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement

Reduced expression and rearrangement of this gene have been detected in various cancers

MUC5B Polyclonal Antibody, 50ul Liquid Handling &Storage The high mobility group nucleosomeThis gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS

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