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RBBP6 Polyclonal Antibody, 100ul Bacterial Expression Expression of this gene may

SKU: 22692554341

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RBBP6 Polyclonal Antibody, 100ul Bacterial Expression Expression of this gene mayThe retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.

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Description

Expression of this gene may be downregulated in colon and rectal cancer

Together with RAB11A

Allelic variations in this gene have been associated with atopy

An important paralog of this gene is MPND

RBBP6 Polyclonal Antibody, 100ul Bacterial Expression Expression of this gene mayThe retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.

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