VPS4B Polyclonal Antibody, 20ul RNA Synthesis A paralog of this gene

A paralog of this gene which also has a trypsin-like peptidase domain

Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease

Activation of T cells through the T cell receptor (TCR) results in tyrosine phosphorylation of CD5

the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs

VPS4B Polyclonal Antibody, 20ul RNA Synthesis A paralog of this geneThe protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog.