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DDR1 Polyclonal Antibody, 100ul[BT-AP02536] Pipette Micro Tips Mutations in this gene result

SKU: 28591225863

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DKK123.75 DKK171.75

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DDR1 Polyclonal Antibody, 100ul[BT-AP02536] Pipette Micro Tips Mutations in this gene resultReceptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. Discoidin domain receptor tyrosine kinase 1 encoded by DDR1 belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen.

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Description

Mutations in this gene result in primary cilia abnormalities and classical Joubert syndrome

where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction

Note that the nine exons of both the telomeric and centromeric copies are des

Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation| and an association of this gene with myocardial infarction has been demonstrated

DDR1 Polyclonal Antibody, 100ul[BT-AP02536] Pipette Micro Tips Mutations in this gene resultReceptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. Discoidin domain receptor tyrosine kinase 1 encoded by DDR1 belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen.

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