Phospho-AIRE-1 (S156) Polyclonal Antibody, 20ul Buffers & Solutions Some individuals with the poor

Some individuals with the poor metabolizer phenotype have no functional protein since they carry 2 null alleles whereas in other individuals the gene is absent

Members of the PAX family typically contain a paired box domain and a paired-type homeodomain

DEFA3 differs from defensin

bone resorption

Phospho-AIRE-1 (S156) Polyclonal Antibody, 20ul Buffers & Solutions Some individuals with the poorAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and