p53 Polyclonal Antibody, 50ul[BT-AP06808] Antibody Development Alternative splicing of DYRK1A generates

Alternative splicing of DYRK1A generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region

Multiple alternatively spliced transcript variants encoding different isoforms have been identified in CD4

the second at Ser-46

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p53 Polyclonal Antibody, 50ul[BT-AP06808] Antibody Development Alternative splicing of DYRK1A generatesTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.