ASAP2 Polyclonal Antibody, 20ul Molecular Weight Markers AURKB (aurora kinase B) encodes

AURKB (aurora kinase B) encodes a member of the aurora kinase subfamily of serine/threonine kinases

It activates the urokinase-type plasminogen activator

Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa

It is proposed to play a role in pathological processes| such as cancer| inflammatory diseases| renal diseases| and Alzheimer's disease

ASAP2 Polyclonal Antibody, 20ul Molecular Weight Markers AURKB (aurora kinase B) encodesThis gene encodes a multidomain protein containing an N terminal alpha helical region with a coiled coil motif, followed by a pleckstrin homology (PH) domain, an Arf GAP domain, an ankyrin homology region, a proline rich region, and a C terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2 beta (PYK2). The encoded protein forms a stable complex