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TGM5 Rabbit Polyclonal Antibody, 50ul Polyclonal Antibody Preparation PXN encodes a cytoskeletal protein

SKU: 31386827327

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PLN162.00 PLN199.00

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TGM5 Rabbit Polyclonal Antibody, 50ul Polyclonal Antibody Preparation PXN encodes a cytoskeletal proteinThis gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross links between glutamine and lysine residues often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome.

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Description

PXN encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion)

This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb)

The encoded protein is secreted and may be involved in desquamation in the epidermis

which contains up to 10 non-ATPase subunits

TGM5 Rabbit Polyclonal Antibody, 50ul Polyclonal Antibody Preparation PXN encodes a cytoskeletal proteinThis gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross links between glutamine and lysine residues often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome.

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