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DSCR 1 Polyclonal Antibody, 50ul Molecular Biology |PTM:The trimeric structure of the

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DSCR 1 Polyclonal Antibody, 50ul Molecular Biology |PTM:The trimeric structure of theRegulator of calcineurin 1 encoded by RCAN1 interacts with calcineurin A and inhibits calcineurin dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of RCAN1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.

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Description

|PTM:The trimeric structure of the NC1 domains may be stabilized by covalent bonds between Lys and Met residues

each with a specific pattern of ligand binding and tissue distribution

Diseases associated with GPR158 include smallpox

CDC25B has oncogenic properties

DSCR 1 Polyclonal Antibody, 50ul Molecular Biology |PTM:The trimeric structure of theRegulator of calcineurin 1 encoded by RCAN1 interacts with calcineurin A and inhibits calcineurin dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of RCAN1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.

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