VPS45 Rabbit Polyclonal Antibody, 100ul Vacuum Filter Mutations in this gene are

Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens

is widely expressed

This gene encodes a member of the highly conserved cyclin C subfamily

It is thought to be a functional relative of PPAR-gamma coactivator 1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals

VPS45 Rabbit Polyclonal Antibody, 100ul Vacuum Filter Mutations in this gene areVesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family and shows a high degree of sequence similarity to mouse rat and yeast Vps45. The exact function of this gene is not known but its high expression in