TAF2 Polyclonal Antibody, 50ul Liquid Storage Consumables Interacts with NCOA3| NCOA5 and

Interacts with NCOA3| NCOA5 and NCOA6 coactivators| leading to a strong increase of transcription of target genes

Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS)

miscellaneous:The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the MLL3 gene

Among its related pathways are Gene Expression and Direct p53 effectors

TAF2 Polyclonal Antibody, 50ul Liquid Storage Consumables Interacts with NCOA3| NCOA5 andInitiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA binding protein (TBP) and a group of