AMPK Alpha1 Monoclonal Antibody, 50ul[BT-MCA0156] DNA Libraries Synthesis a POZ/zinc finger transcription repressor

a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis

Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis

Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases

This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase

AMPK Alpha1 Monoclonal Antibody, 50ul[BT-MCA0156] DNA Libraries Synthesis a POZ/zinc finger transcription repressorThe protein encoded by this gene belongs to the ser thr protein kinase family. It is the catalytic subunit of the 5' prime AMP activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that