HEN1/2 Polyclonal Antibody, 50ul Molecular Biology Required for collagen VII (COL7A1)

Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers

The encoded protein undergoes a change in conformational state and activity

The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol

It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN

HEN1/2 Polyclonal Antibody, 50ul Molecular Biology Required for collagen VII (COL7A1)The helix loop helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC, LYL1, E2A, and SCL.