Rb(Phospho Ser788) Polyclonal Antibody, 20ul Antibody Development Several transcript variants encoding two

Several transcript variants encoding two different isoforms have been found for ERF

an important hormone and neurotransmitter

it is seen within the basement membrane of the dermal-epidermal junction at points of nerve penetration

Among its related pathways are Activation of cAMP-Dependent PKA and G-AlphaQ Signaling

Rb(Phospho Ser788) Polyclonal Antibody, 20ul Antibody Development Several transcript variants encoding twoThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.