Mouse Glycogen Synthase Kinase-3 Beta, GSK3B ELISA Kit, 96T Purification This gene encodes an abundant

This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails

This protein is activated by PI3-kinase

It mediates the cellular uptake of transcobalamin bound cobalamin (vitamin B12)

Alternatively spliced transcript variants encoding different protein isoforms have been described

Mouse Glycogen Synthase Kinase-3 Beta, GSK3B ELISA Kit, 96T Purification This gene encodes an abundantConstitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen Synthase (GYS1 or GYS2), EIF2B, CTNNB1 beta catenin, APC, AXIN1, DPYSL2 CRMP2, JUN, NFATC1 NFATC, MAPT TAU and MACF1. Requires primed phosphorylation of the majority of its substrates. In skeletal muscle, contributes to