Rb(Phospho Ser249) Polyclonal Antibody, 50ul Immune Repertoire Sequencing these family members can likely

these family members can likely stimulate calmodulin-dependent kinase II and the protein phosphatase calcineurin

These kinases are involved in the regulation of cell growth| differentiation and metabolism

Interacts with Machupo arenavirus GPC

Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling

Rb(Phospho Ser249) Polyclonal Antibody, 50ul Immune Repertoire Sequencing these family members can likelyThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.