Rat G-protein Coupled Estrogen Receptor 1, GPER1, 96T Oligo Pool CLCN6 encodes a member of

CLCN6 encodes a member of the voltage-dependent chloride channel protein family

and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus

The gene has a pseudogene located on chromosome 3

pre-chylomicrons and pre-VLDLs

Rat G-protein Coupled Estrogen Receptor 1, GPER1, 96T Oligo Pool CLCN6 encodes a member ofG protein coupled estrogen receptor that binds to 17 beta estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilization and tyrosine kinase Src inducing the release of heparin bound epidermal growth factor (HB EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as