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Paxillin(Phospho Tyr118) Polyclonal Antibody, 20ul Measuring Instruments The encoded protein may play

SKU: 36305010183

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Paxillin(Phospho Tyr118) Polyclonal Antibody, 20ul Measuring Instruments The encoded protein may playThis gene encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID: 9054445).

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Description

The encoded protein may play a role in the developing kidney

Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK)

Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression| and the zinc-fingers comprise the DNA binding domain

In response to BMP ligands

Paxillin(Phospho Tyr118) Polyclonal Antibody, 20ul Measuring Instruments The encoded protein may playThis gene encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID: 9054445).

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