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Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy and possesses ubiquitin ligase E3

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Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy and possesses ubiquitin ligase E3The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB) bladder cancer and osteogenic sarcoma.

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Description

and possesses ubiquitin ligase E3 activity

thymus and fetal liver

The encoded protein may be involved in sensory neuron regulation and in the modulation of pain

Another member of the CHP subfamily

Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy and possesses ubiquitin ligase E3The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB) bladder cancer and osteogenic sarcoma.

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