RAGP1 Polyclonal Antibody, 50ul Capsule Filter and with Senior-Loken syndrome type

and with Senior-Loken syndrome type 4

The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature

however| imprinting of the human gene may be polymorphic| as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611)

strong ectopic expression has been detected in ovarian adenocarcinoma

RAGP1 Polyclonal Antibody, 50ul Capsule Filter and with Senior-Loken syndrome typeThis gene encodes a protein that associates with the nuclear pore complex and participates in the regulation of nuclear transport. The encoded protein interacts with Ras related nuclear protein 1 (RAN) and regulates guanosine triphosphate (GTP) binding and exchange. Alternative splicing results in multiple transcript variants.