LDOC1 Polyclonal Antibody, 100ul Vessels Several transcript variants encoding different

Several transcript variants encoding different isoforms of supervillin have been described

The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia

RBX1 and VHL

The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin

LDOC1 Polyclonal Antibody, 100ul Vessels Several transcript variants encoding differentThe leucine zipper down regulated in cancer 1 encoded by LDOC1 contains a leucine zipper like motif and a proline rich region that shares marked similarity with an SH3 binding domain. The protein localizes to the nucleus and is down regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF kappaB). The gene has been proposed as a tumor suppressor gene whose protein product