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ER Alpha Monoclonal Antibody, 50ul[BT-MCA0516] Enzymes It stabilizes APP and inhibits

SKU: 38835646907

4.6
USD185.00 USD232.00

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ER Alpha Monoclonal Antibody, 50ul[BT-MCA0516] Enzymes It stabilizes APP and inhibitsThis gene encodes an estrogen receptor, a ligand activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen

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Description

It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients

Sumoylation of mHTT by this protein may cause degeneration of the striatum

Excess cellular ceramide can trigger antimitogenic signals and induce apoptosis

including the BRCA1-A complex and the BRISC complex

ER Alpha Monoclonal Antibody, 50ul[BT-MCA0516] Enzymes It stabilizes APP and inhibitsThis gene encodes an estrogen receptor, a ligand activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen

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