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JAZF1 Rabbit Polyclonal Antibody, 20ul Bottles The encoded protein may play

SKU: 3960472312

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JAZF1 Rabbit Polyclonal Antibody, 20ul Bottles The encoded protein may playThis gene encodes a nuclear protein with three C2H2 type zinc fingers and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however not all variants have been fully characterized

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Description

The encoded protein may play a critical role in the regulation of apoptosis

and cancer metastasis

|PTM:Monoubiquitination of Lys-122 gives a specific tag for epigenetic transcriptional repression

The encoded protein is found to be associated with centromeres of mitotic HeLa cells| which suggests that this protein is a functional homolog of yeast Nuf2

JAZF1 Rabbit Polyclonal Antibody, 20ul Bottles The encoded protein may playThis gene encodes a nuclear protein with three C2H2 type zinc fingers and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however not all variants have been fully characterized

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