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AES Polyclonal Antibody, 50ul Buffer Solutions The chondroitin sulfate proteoglycan NG2

SKU: 40639133003

4.5
USD162.00 USD195.00

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AES Polyclonal Antibody, 50ul Buffer Solutions The chondroitin sulfate proteoglycan NG2The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms

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Description

The chondroitin sulfate proteoglycan NG2 is a type I membrane protein expressed by subpopulations of glia including oligodendroglial precursor cells and a variety of tumor cells

Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter

a transmembrane region and a highly conserved cytoplasmic tail

PLD4 (Phospholipase D Family Member 4) is a Protein Coding gene

AES Polyclonal Antibody, 50ul Buffer Solutions The chondroitin sulfate proteoglycan NG2The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms

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