TM55A Rabbit Polyclonal Antibody, 50ul sgRNA customized design The protein encoded by this

The protein encoded by this gene catalyzes the CTP-mediated phosphorylation of dolichol| and is involved in the synthesis of Dol-P-Man| which is an essential glycosyl carrier lipid for C- and O-mannosylation| N- and O-linked glycosylation of proteins| and for the biosynthesis of glycosyl phosphatidylinositol anchors in endoplasmic reticulum

The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II)| which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation

11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia

The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways

TM55A Rabbit Polyclonal Antibody, 50ul sgRNA customized design The protein encoded by thisTMEM55A catalyzes the degradation of phosphatidylinositol 4 5 bisphosphate (PtdIns 4 5 P2) by removing the 4 phosphate (Ungewickell et al. 2005