TRM6 Rabbit Polyclonal Antibody, 20ul Cellular Function Assays thus down-regulating ER-to-Golgi transport of

thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis

Mutations in COL18A1 are associated with Knobloch syndrome

The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis

and inhibits the latter's degradation

TRM6 Rabbit Polyclonal Antibody, 20ul Cellular Function Assays thus down-regulating ER-to-Golgi transport ofThis gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase which is involved in the posttranslational modification that produces the modified nucleoside 1 methyladenosine in tRNAs. Modified 1 methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. Alternative splicing results in