HES-6 Polyclonal Antibody, 50ul Gene Synthesis disease:Chromosomal aberrations involving FOXO1 are

disease:Chromosomal aberrations involving FOXO1 are a cause of rhabdomyosarcoma 2 (RMS2)

which was initially cloned from human dermal papilla cells and is evolutionally conserved from drosophila through to humans

May be required for pre-mRNA splicing

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HES-6 Polyclonal Antibody, 50ul Gene Synthesis disease:Chromosomal aberrations involving FOXO1 areHES6 encodes a member of a subfamily of basic helix loop helix transcription repressors that have homology to the Drosophila enhancer of split genes. Members of HES6 family regulate cell differentiation in numerous cell types. Transcription cofactor HES 6 encoded by HES6 functions as a cofactor, interacting with other transcription factors through a tetrapeptide domain in its C terminus. Alternatively spliced transcript variants encoding different