SPP2A Rabbit Polyclonal Antibody, 20ul ssDNA Synthesis Patients with dermatomyositis develop antibodies

Patients with dermatomyositis develop antibodies against this protein

Associates with the 9-1-1 complex

The heat shock transcription factor 2 encoded by HSF2 belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription

Members of PAX8 family typically encode proteins that contain a paired box domain

SPP2A Rabbit Polyclonal Antibody, 20ul ssDNA Synthesis Patients with dermatomyositis develop antibodiesThis gene encodes a member of the GXGD family of aspartic proteases which are transmembrane proteins with two conserved catalytic motifs localized within the membrane spanning regions as well as a member of the signal peptide peptidase like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15.